4 accepted papers
Automated microinjection systems for suspension cells have been studied for years. Nevertheless, microinjection systems for adherent cells still suffer from laborious manual operations and low productivity. This paper presents a new automated microinjection system with high productivity for adherent
Intracellular surgery suffers from a low success rate due to the lack of three-dimensional (3-D) position feedback of selected organelles. In this study, we developed a novel robot-aided microscopy system and 3-D reconstruction algorithm to conduct intracellular surgery with 3-D information. A serie
Introducing alterations in the mtDNA sequence is challenging but needed for potential therapies and basic studies. Direct microinjection of mitochondria into small cells has been considered inefficient and impractical. To address this issue, we present a highly efficient and precise robotic approach…
In this paper, we present a precise robot-aided single-cell surgery system to perform single-cell biopsy for cells <25 μm in diameter. A microfluidic chip is designed to arrange upto 100 individual cells in an array. A micropipette mounted onto a 3-DOF micromanipulator and a computer mouse-operated…