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James K. Mills

4 accepted papers

2024

Automating Trophectoderm Cells Aspiration and Separation in Embryo Biopsy at the Blastocyst Stage: A Vision-Based Control Approach

IROS 2024poster

Reproductive medicine has recently witnessed significant advancements, particularly in vitro fertilization (IVF). One crucial aspect of IVF involves the extraction of cellular material and its analysis to maximize the chance of successful implantation. This work highlights the development and applic…

Cited by 0SourceScholar
2017

A high-precision robot-aided single-cell biopsy system

ICRA 2017poster

In this paper, we present a precise robot-aided single-cell surgery system to perform single-cell biopsy for cells <25 μm in diameter. A microfluidic chip is designed to arrange upto 100 individual cells in an array. A micropipette mounted onto a 3-DOF micromanipulator and a computer mouse-operated…

Cited by 16SourceScholar
2016

Cleavage-stage embryo rotation tracking and automated micropipette control: Towards automated single cell manipulation

IROS 2016poster

Micromanipulation of individual biological cells, such as embryos during preimplantation genetic diagnosis (PGD), is a delicate and time-consuming task. Two major procedures in PGD include the rotation of the embryo to gain a more favorable position for zona breaching, and the extraction of a blasto…

Cited by 15SourceScholar
2015

Modelling and control of optical manipulation for cell rotation

ICRA 2015poster

Optical tweezers has become a powerful tool in automated cell transportation control and has been used in a variety of biological applications. The use of optical tweezers for cell surgery has great potential for various biomedical applications such as microinjection, organelle extraction and modifi…

Cited by 15SourceScholar