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Jianwei Zhu

2 accepted papers

2026

FlexProtein: Joint Sequence and Structure Pretraining for Protein Modeling

ICLR 2026poster

Protein foundation models have advanced rapidly, with most approaches falling into two dominant paradigms. Sequence-only language models (e.g., ESM-2) capture sequence semantics at scale but lack structural grounding. MSA-based predictors (e.g., AlphaFold 2/3) achieve accurate folding by exploiting…

Cited by 0SourceScholar
2021

Co-evolution Transformer for Protein Contact Prediction

NeurIPS 2021poster

Proteins are the main machinery of life and protein functions are largely determined by their 3D structures. The measurement of the pairwise proximity between amino acids of a protein, known as inter-residue contact map, well characterizes the structural information of a protein. Protein contact pre…