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Haiguang Liu

2 accepted papers

2026

FlexProtein: Joint Sequence and Structure Pretraining for Protein Modeling

ICLR 2026poster

Protein foundation models have advanced rapidly, with most approaches falling into two dominant paradigms. Sequence-only language models (e.g., ESM-2) capture sequence semantics at scale but lack structural grounding. MSA-based predictors (e.g., AlphaFold 2/3) achieve accurate folding by exploiting…

Cited by 0SourceScholar
2026

Unbiased Dynamic Pruning for Efficient Group-Based Policy Optimization

ICML 2026poster

Group Relative Policy Optimization (GRPO) effectively scales LLM reasoning but incurs prohibitive computational costs due to its extensive group-based sampling requirement. While recent selective data utilization methods can mitigate this overhead, they could induce estimation bias by altering the u…

Cited by 0SourceScholar