C2MIL: Synchronizing Semantic and Topological Causalities in Multiple Instance Learning for Robust and Interpretable Survival Analysis
Graph-based Multiple Instance Learning (MIL) is widely used in survival analysis with Hematoxylin and Eosin (H&E)-stained whole slide images (WSIs) due to its ability to capture topological information. However, variations in staining and scanning can introduce semantic bias, while topological subgr…