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Yongjie Xu

8 accepted papers

2026

HDTree: Generative Modeling of Cellular Hierarchies for Robust Lineage Inference

ICML 2026poster

In single-cell research, tracing and analyzing high-throughput single-cell differentiation trajectories is crucial for understanding biological processes. Key to this is the robust modeling of hierarchical structures that govern cellular development. Traditional methods face limitations in computati…

Cited by 0SourceScholar
2024

Learning Complete Protein Representation by Dynamically Coupling of Sequence and Structure

NeurIPS 2024poster

Learning effective representations is imperative for comprehending proteins and deciphering their biological functions. Recent strides in language models and graph neural networks have empowered protein models to harness primary or tertiary structure information for representation learning. Neverthe…

Cited by 0SourcePDFScholar
2024

PhyloGen: Language Model-Enhanced Phylogenetic Inference via Graph Structure Generation

NeurIPS 2024poster

Phylogenetic trees elucidate evolutionary relationships among species, but phylogenetic inference remains challenging due to the complexity of combining continuous (branch lengths) and discrete parameters (tree topology). Traditional Markov Chain Monte Carlo methods face slow convergence and co…

Cited by 2SourcePDFScholar
2024

ProtGO: Function-Guided Protein Modeling for Unified Representation Learning

NeurIPS 2024poster

Protein representation learning is indispensable for various downstream applications of artificial intelligence for bio-medicine research, such as drug design and function prediction. However, achieving effective representation learning for proteins poses challenges due to the diversity of data moda…

Cited by 0SourcePDFScholar
2023

Temporal Attention Unit: Towards Efficient Spatiotemporal Predictive Learning

CVPR 2023poster

Spatiotemporal predictive learning aims to generate future frames by learning from historical frames. In this paper, we investigate existing methods and present a general framework of spatiotemporal predictive learning, in which the spatial encoder and decoder capture intra-frame features and the mi…

2023

Wordreg: Mitigating the Gap between Training and Inference with Worst-Case Drop Regularization

ICASSP 2023accepted

Dropout has emerged as one of the most frequently used techniques for training deep neural networks (DNNs). Although effective, the sampled sub-model by random dropout during training is inconsistent with the full model (without dropout) during inference. To mitigate this undesirable gap, we propose…

Cited by 0SourceScholar
2022

Conditional Local Convolution for Spatio-Temporal Meteorological Forecasting

AAAI 2022technical

Spatio-temporal forecasting is challenging attributing to the high nonlinearity in temporal dynamics as well as complex location-characterized patterns in spatial domains, especially in fields like weather forecasting. Graph convolutions are usually used for modeling the spatial dependency in meteor…