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Chang Yu

23 accepted papers

2026

CDBridge: A Cross-omics Post-training Bridge Strategy for Context-aware Biological Modeling

ICLR 2026poster

Linking genomic DNA to quantitative, context-specific expression remains a central challenge in computational biology. Current foundation models capture either tissue context or sequence features, but not both. Cross-omics systems, in turn, often overlook critical mechanisms such as alternative spli…

Cited by 0SourceScholar
2026

CVF-DLO: Cross-Visual-Field Branched Deformable Linear Objects Route Estimation

ICRA 2026poster

The perception of deformable linear objects (DLOs) poses significant challenges in robotic manipulation. Crossovers, mergings, and bifurcations of multiple DLOs complicate the identification of individual DLO physical instances. Furthermore, DLOs are often too large to be captured by a single camera…

Cited by 0codeScholar
2026

Doloris: Dual Conditional Diffusion Implicit Bridges with Sparsity Masking Strategy for Unpaired Single-Cell Perturbation Estimation

ICLR 2026poster

Estimating single-cell responses across various perturbations facilitates the identification of key genes and enhances drug screening, significantly boosting experimental efficiency. However, single-cell sequencing is a destructive process, making it impossible to capture the same cell's phenotype b…

Cited by 0SourcecodeScholar
2026

Geometric Flow Grounding: A Unified Manifold Decoupling Framework for Dynamics Discovery and Verification

ICML 2026oral

Modeling complex dynamics from observational data is fundamental to scientific discovery and artificial intelligence. However, existing approaches ranging from Neural ODEs to diffusion models are often plagued by the entanglement of static state representations and instantaneous motion, leading to a…

Cited by 0SourceScholar
2026

HDTree: Generative Modeling of Cellular Hierarchies for Robust Lineage Inference

ICML 2026poster

In single-cell research, tracing and analyzing high-throughput single-cell differentiation trajectories is crucial for understanding biological processes. Key to this is the robust modeling of hierarchical structures that govern cellular development. Traditional methods face limitations in computati…

Cited by 0SourceScholar
2026

MergeDNA: Context-Aware Genome Modeling with Dynamic Tokenization Through Token Merging

AAAI 2026technical

Modeling genomic sequences faces two unsolved challenges: the information density varies widely across different regions, while there is no clearly defined minimum vocabulary unit. Relying on either four primitive bases or independently designed DNA tokenizers, existing approaches with naive masked

Cited by 0SourcePDFScholar
2026

Right-Side-Out: Learning Zero-Shot Sim-To-Real Garment Reversal

ICRA 2026poster

Turning garments right-side out is a challenging manipulation task: it is highly dynamic, entails rapid contact changes, and is subject to severe visual occlusion. We introduce Right-Side-Out, a zero-shot sim-to-real framework that effectively solves this challenge by exploiting task structures. We …

2026

SYNC: Measuring and Advancing Synthesizability in Structure-Based Drug Design

ICLR 2026poster

Designing 3D ligands that bind to a given protein pocket with high affinity is a fundamental task in Structure-Based Drug Design (SBDD). However, the lack of synthesizability of 3D ligands has been hindering progress toward experimental validation; moreover, computationally evaluating synthesizabili…

Cited by 0SourcecodeScholar
2026

SteinsGate: Adding Causality to Diffusions for Long Video Generation via Path Integral

ICLR 2026poster

Video generation has advanced rapidly, but current models remain limited to short clips, far from the length and complexity of real-world narratives. Long video generation is thus both important and challenging. Existing approaches either attempt to extend the modeling length of video diffusion mode…

Cited by 0SourceScholar
2025

A Convex Formulation of Material Points and Rigid Bodies with GPU-Accelerated Async-Coupling for Interactive Simulation

IROS 2025

We present a novel convex formulation that weakly couples the Material Point Method (MPM) with rigid body dynamics through frictional contact, optimized for efficient GPU parallelization. Our approach features an asynchronous time-splitting scheme to integrate MPM and rigid body dynamics under diffe

Cited by 3SourceScholar
2025

ARM: Appearance Reconstruction Model for Relightable 3D Generation

CVPR 2025highlight

Recent image-to-3D reconstruction models have greatly advanced geometry generation, but they still struggle to faithfully generate realistic appearance. To address this, we introduce ARM, a novel method that reconstructs high-quality 3D meshes and realistic appearance from sparse-view images. The co…

2025

CVF-DLO: Cross-Visual-Field Branched Deformable Linear Objects Route Estimation

RA-L 2025

The perception of deformable linear objects (DLOs) poses significant challenges in robotic manipulation. Crossovers, mergings, and bifurcations of multiple DLOs complicate the identification of individual DLO physical instances. Furthermore, DLOs are often too large to be captured by a single camera

Cited by 1SourcecodeScholar
2025

DaCapo: Score Distillation as Stacked Bridge for Fast and High-quality 3D Editing

CVPR 2025poster

Score Distillation Sampling (SDS) has been successfully extended to text-driven 3D scene editing with 2D pretrained diffusion models. However, SDS-based editing methods suffer from lengthy optimization processes with slow inference and low quality. We attribute the issue of lengthy optimization to t…

Cited by 0SourcePDFScholar
2025

Embedded IPC: Fast and Intersection-Free Simulation in Reduced Subspace for Robot Manipulation

ICRA 2025

Physics-based simulation is essential for developing and evaluating robot manipulation policies, particularly in scenarios involving deformable objects and complex contact interactions. However, existing simulators often struggle to balance computational efficiency with numerical accuracy, especiall

Cited by 2SourceScholar
2025

GRAPE: Heterogeneous Graph Representation Learning for Genetic Perturbation with Coding and Non-Coding Biotype

IJCAI 2025

Predicting genetic perturbations enables the identification of potentially crucial genes prior to wet-lab experiments, significantly improving overall experimental efficiency. Since genes are the foundation of cellular life, building gene regulatory networks (GRN) is essential to understand and pred

2025

GRIP: A General Robotic Incremental Potential Contact Simulation Dataset for Unified Deformable-Rigid Coupled Grasping

IROS 2025

Grasping is fundamental to robotic manipulation, and recent advances in large-scale grasping datasets have provided essential training data and evaluation benchmarks, accelerating the development of learning-based methods for robust object grasping. However, most existing datasets exclude deformable

Cited by 3SourcecodeScholar
2025

Gaussian Splashing: Unified Particles for Versatile Motion Synthesis and Rendering

CVPR 2025poster

We demonstrate the feasibility of integrating physics-based animations of solids and fluids with 3D Gaussian Splatting (3DGS) to create novel effects in virtual scenes reconstructed using 3DGS. Leveraging the coherence of the Gaussian Splatting and Position-Based Dynamics (PBD) in the underlying rep…

Cited by 10SourcePDFScholar
2025

Hipandas: Hyperspectral Image Joint Denoising and Super-Resolution by Image Fusion with the Panchromatic Image

ICCV 2025poster

Hyperspectral images (HSIs) are frequently noisy and of low resolution due to the constraints of imaging devices. Recently launched satellites can concurrently acquire HSIs and panchromatic (PAN) images, enabling the restoration of HSIs to generate clean and high-resolution imagery through fusing PA…

2025

MergeVQ: A Unified Framework for Visual Generation and Representation with Disentangled Token Merging and Quantization

CVPR 2025poster

Masked Image Modeling (MIM) with Vector Quantization (VQ) has achieved great success in both self-supervised pre-training and image generation. However, most existing methods struggle to address the trade-off in the shared latent space for generation quality vs. representation learning and efficienc…

2025

Taccel: Scaling Up Vision-based Tactile Robotics via High-performance GPU Simulation

NeurIPS 2025spotlight

Tactile sensing is crucial for achieving human-level robotic capabilities in manipulation tasks. As a promising solution, Vision-based Tactile Sensors (VBTSs) offer high spatial resolution and cost-effectiveness, but present unique challenges in robotics for their complex physical characteristics an…

Cited by 0SourcecodeScholar
2023

Graphics Capsule: Learning Hierarchical 3D Face Representations From 2D Images

CVPR 2023poster

The function of constructing the hierarchy of objects is important to the visual process of the human brain. Previous studies have successfully adopted capsule networks to decompose the digits and faces into parts in an unsupervised manner to investigate the similar perception mechanism of neural ne…

Cited by 7SourcePDFScholar
2022

HP-Capsule: Unsupervised Face Part Discovery by Hierarchical Parsing Capsule Network

CVPR 2022poster

Capsule networks are designed to present the objects by a set of parts and their relationships, which provide an insight into the procedure of visual perception. Although recent works have shown the success of capsule networks on simple objects like digits, the human faces with homologous structures…

Cited by 22PDFScholar
2020

Beyond 3DMM Space: Towards Fine-grained 3D Face Reconstruction

ECCV 2020poster

Recently, deep learning based 3D face reconstruction methods have shown promising results in both quality and efficiency. However, most of their training data is constructed by 3D Morphable Model, whose space spanned is only a small part of the shape space. As a result, the reconstruction results lo…