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Yuan Pei

3 accepted papers

2026

CryoACE: An Atom-centric Framework for Accurate and Automated Model Building in Cryo-EM

ICML 2026poster

Protein automodeling from cryo-EM density maps faces unique challenges in enforcing physicochemical validity and managing conformational heterogeneity. Current solvers are often limited to static predictions or require computationally intensive heuristic searches. We present CryoACE, an end-to-end f…

Cited by 0SourceScholar
2025

CryoFastAR: Fast Cryo-EM Ab initio Reconstruction Made Easy

ICCV 2025poster

Pose estimation from unordered images is fundamental for 3D reconstruction, robotics, and scientific imaging. Recent geometric foundation models, such as DUSt3R, enable end-to-end dense 3D reconstruction but remain underexplored in scientific imaging fields like cryo-electron microscopy (cryo-EM) fo…

Cited by 0SourcePDFScholar
2024

DRACO: A Denoising-Reconstruction Autoencoder for Cryo-EM

NeurIPS 2024poster

Foundation models in computer vision have demonstrated exceptional performance in zero-shot and few-shot tasks by extracting multi-purpose features from large-scale datasets through self-supervised pre-training methods. However, these models often overlook the severe corruption in cryogenic electron…

Cited by 1SourcePDFScholar