2026
CryoACE: An Atom-centric Framework for Accurate and Automated Model Building in Cryo-EM
ICML 2026poster
Protein automodeling from cryo-EM density maps faces unique challenges in enforcing physicochemical validity and managing conformational heterogeneity. Current solvers are often limited to static predictions or require computationally intensive heuristic searches. We present CryoACE, an end-to-end f…