38 accepted papers
Reinforcement learning (RL) has become a dominant paradigm for enhancing LLMs' reasoning capabilities. However, RL algorithms with PPO-Clip are inherently limited by exploration collapse. Subsequent works remain primarily heuristic and fail to identify the essential cause of PPO-Clip’s failure. This…
Autonomous driving needs fast, scalable 4D reconstruction and re-simulation for training and evaluation, yet most methods for dynamic driving scenes still rely on per-scene optimization, known camera calibration, or short frame windows, making them slow and impractical. We revisit this problem from
A significant portion of disease-relevant proteins remain undruggable due to shallow, flexible, or otherwise ill-defined binding pockets that hinder conventional molecule screening. Fragment-based drug discovery (FBDD) offers a promising alternative, as small, low-complexity fragments can flexibly e…
Protein-ligand binding prediction is central to virtual screening and affinity ranking, two fundamental tasks in drug discovery. While recent retrieval-based methods embed ligands and protein pockets into Euclidean space for similarity-based search, the geometry of Euclidean embeddings often fails t
Despite improvements by length extrapolation, efficient attention and memory modules, handling infinitely long documents without performance degradation during extrapolation remains the ultimate challenge in long-text processing. To solve this problem, We introduce a novel agent workflow, \method, w…
Differentially Private Stochastic Gradient Descent (DP-SGD) and its variants like DP-Adam ensure data privacy by injecting noise into per-sample gradients. Although effective with large private datasets, their performance degrades significantly when private training data is limited. Recent works lev…
Despite the sustained scaling on model capacity and data acquisition, Vision–Language–Action (VLA) models remain brittle in contact-rich and dynamic manipulation tasks, where minor execution deviations can compound into failures. While reinforcement learning (RL) offers a principled path to robustne…
Virtual screening (VS) is an essential task in drug discovery, focusing on the identification of small-molecule ligands that bind to specific protein pockets. Existing deep learning methods, from early regression models to recent contrastive learning approaches, primarily rely on structural data whi
Vector-quantized variational autoencoders (VQ-VAEs) are discrete autoencoders that compress images into discrete tokens. However, they are difficult to train due to discretization. In this paper, we propose a simple yet effective technique dubbed __Gaussian Quant (GQ)__, which first trains a Gaussia…
Successful generalist Vision-Language-Action (VLA) models that rely on effective training across diverse robotic platforms with large-scale, cross-embodiment, heterogeneous datasets. To facilitate and leverage the heterogeneity in rich, diverse robotic data sources, we propose a novel Soft Prompt ap…
Virtual screening (VS) is a critical component of modern drug discovery, yet most existing methods—whether physics-based or deep learning-based—are developed around *holo* protein structures with known ligand-bound pockets. Consequently, their performance degrades significantly on *apo* or predicted…
Structure-guided molecular generation is pivotal in early-stage drug discovery, enabling the design of compounds tailored to specific protein targets. However, despite recent advances in 3D generative modeling, particularly in improving docking scores, these methods often produce rare and intrinsica…
Substantial quantity and high quality are the golden rules of making a good training dataset with sample privacy protection equally important. Generating synthetic samples that resemble high-quality private data while ensuring Differential Privacy (DP), a formal privacy guarantee, promises scalabili…
Cooperative perception enhances the individual perception capabilities of autonomous vehicles (AVs) by providing a comprehensive view of the environment. However, balancing perception performance and transmission costs remains a significant challenge. Current approaches that transmit regionlevel fea
Inference scaling empowers LLMs with unprecedented reasoning ability, with reinforcement learning as the core technique to elicit complex reasoning. However, key technical details of state-of-the-art reasoning LLMs are concealed (such as in OpenAI o1 blog and DeepSeek R1 technical report), thus the…
Occupancy prediction provides critical geometric and semantic understanding for robotics but faces efficiency-accuracy trade-offs. Current dense methods suffer computational waste on empty voxels, while sparse query-based approaches lack robustness in diverse and complex indoor scenes. In this paper
In autonomous driving, The perception capabilities of the ego-vehicle can be improved with roadside sensors, which can provide a holistic view of the environment. However, existing monocular detection methods designed for vehicle cameras are not suitable for roadside cameras due to viewpoint domain
We present InvRGB+L, a novel inverse rendering model that reconstructs large, relightable, and dynamic scenes from a single RGB+LiDAR sequence. Conventional inverse graphics methods rely primarily on RGB observations and use LiDAR mainly for geometric information, often resulting in suboptimal mater…
Recently, perceptual image compression has achieved significant advancements, delivering high visual quality at low bitrates for natural images. However, for screen content, existing methods often produce noticeable artifacts when compressing text. To tackle this challenge, we propose versatile perc…
Small molecules are vital to modern medicine, and accurately predicting their bioactivity against protein targets is crucial for therapeutic discovery and development. However, current machine learning models often rely on spurious features, leading to biased outcomes. Notably, a simple pocket-only…
Recent advances in structure-based drug design (SBDD) have produced surprising results, with models often generating molecules that achieve better Vina docking scores than actual ligands. However, these results are frequently overly optimistic due to the limitations of docking score accuracy and the…
Recent advancements in diffusion models have been leveraged to address inverse problems without additional training, and Diffusion Posterior Sampling (DPS) (Chung et al., 2022a) is among the most popular approaches. Previous analyses suggest that DPS accomplishes posterior sampling by approximating…
Multimodal task specification is essential for enhanced robotic performance, where Cross-modality Alignment enables the robot to holistically understand complex task instructions. Directly annotating multimodal instructions for model training proves impractical, due to the sparsity of paired multimo
Training on diverse, internet-scale data is a key factor in the success of recent large foundation models. Yet, using the same recipe for building embodied agents has faced noticeable difficulties. Despite the availability of many crowd-sourced embodied datasets, their action spaces often exhibit si…
Multimodal pretraining is an effective strategy for the trinity of goals of representation learning in autonomous robots: $1)$ extracting both local and global task progressions; $2)$ enforcing temporal consistency of visual representation; $3)$ capturing trajectory-level language grounding. Most ex…
In autonomous driving, cooperative perception makes use of multi-view cameras from both vehicles and infrastructure, providing a global vantage point with rich semantic context of road conditions beyond a single vehicle viewpoint. Currently, two major challenges persist in vehicle-infrastructure coo…
Data-generation based zero-shot learning, although effective in training Small Task-specific Models (STMs) via synthetic datasets generated by Pre-trained Language Models (PLMs), is often limited by the low quality of such synthetic datasets. Previous solutions have primarily focused on single PLM s…
Idempotence is the stability of image codec to re-compression. At the first glance, it is unrelated to perceptual image compression. However, we find that theoretically: 1) Conditional generative model-based perceptual codec satisfies idempotence; 2) Unconditional generative model with idempotence c…
Preference-based reinforcement learning (PbRL) provides a natural way to align RL agents’ behavior with human desired outcomes, but is often restrained by costly human feedback. To improve feedback efficiency, most existing PbRL methods focus on selecting queries to maximally improve the overall qua…
Vertical Federated Learning (VFL) has emerged as a collaborative training paradigm that allows participants with different features of the same group of users to accomplish cooperative training without exposing their raw data or model parameters. VFL has gained significant attention for its research…
In this paper, we consider the problem of bit allocation in Neural Video Compression (NVC). First, we reveal a fundamental relationship between bit allocation in NVC and Semi-Amortized Variational Inference (SAVI). Specifically, we show that SAVI with GoP (Group-of-Picture)-level likelihood is equiv…
We consider the problem of idempotent learned image compression (LIC). The idempotence of codec refers to the stability of codec to re-compression. To achieve idempotence, previous codecs adopt invertible transforms such as DCT and normalizing flow. In this paper, we first identify that invertibilit…
Scene completion refers to obtaining dense scene representation from an incomplete perception of complex 3D scenes. This helps robots detect multi-scale obstacles and analyse object occlusions in scenarios such as autonomous driving. Recent advances show that implicit representation learning can be…
Reward function is essential in reinforcement learning (RL), serving as the guiding signal to incentivize agents to solve given tasks, however, is also notoriously difficult to design. In many cases, only imperfect rewards are available, which inflicts substantial performance loss for RL agents. In…
In offline reinforcement learning (RL), one detrimental issue to policy learning is the error accumulation of deep \textit{Q} function in out-of-distribution (OOD) areas. Unfortunately, existing offline RL methods are often over-conservative, inevitably hurting generalization performance outside dat…
3D scene understanding from point clouds plays a vital role for various robotic applications. Unfortunately, current state-of-the-art methods use separate neural networks for different tasks like object detection or room layout estimation. Such a scheme has two limitations: 1) Storing and running se
Current referring expression comprehension algorithms can effectively detect or segment objects indicated by nouns, but how to understand verb reference is still under-explored. As such, we study the challenging problem of task oriented detection, which aims to find objects that best afford an actio…