30 accepted papers
Magnetically actuated micro/nanorobot swarms have exhibited considerable promise for targeted biomedical delivery and localized therapies, attributed to their advantages of remote manipulation and robust penetration through biological tissues. However, achieving the simultaneous enhancement of both …
Space computing devices expand handwritten input from two-dimensional screens into three-dimensional space, providing an unrestricted interactive experience. Due to the high degree of freedom and lack of tactile feedback in in-air handwriting, handwritten characters not only become less legible but
This paper presents an integrated optoelectronic tweezers platform that unifies hydrogel microstructure fabrication with subsequent dynamic microsphere manipulation, enabled by a dual-wavelength optical strategy for seamless and programmable control. Initial tests in low-conductivity aqueous media c…
The programmable assembly and actuation of micro- and nanostructures remain key challenges in the development of micro-robotics. This work presents a programmable assembly and cooperative actuation strategy for heterogeneous microspheres based on optoelectronic tweezers (OET). By employing Ag-PS mic…
Motivated by clinical needs for precise navigation and safety, low-latency and high-precision localization has become a key enabler for capsule robots. A unified magnetic 5-DoF high-precision localization framework for capsule robots is presented. Building on layered multi-source magnetic field mode…
Microfluidic technology is currently a popular approach in the field of single-cell research, which is used to reveal the heterogeneity among cells. However, most of the existing microfluidic technologies for single-cell research lack the ability to control the microenvironment of single cells after
Action segmentation in untrimmed videos is essential for comprehensive video understanding. Despite significant progress in unsupervised methods, capturing both long-range dependencies and short-duration actions simultaneously remains a challenging task. To address this challenge, this paper introdu…
Magnetically controlled micro-nano robots hold revolutionary significance in the clinical targeted treatment of brain tumors. Imaging and tracking miniature robots can provide feedback for precise magnetic field control. The cooperation among micro-nano robots, magnetic field control system, and ima
This paper presents a multi-particle parallel manipulation optoelectronic tweezers system integrated with computer vision technology, enabling the parallel and precise manipulation of dozens of particles. This system significantly enhances manipulation efficiency while maintaining high precision. By
The efficacy of targeted cancer drug therapy is significantly compromised by imprecise drug delivery mechanisms. Micro/nano robots (MNRs), characterized by their controllable motion, present a promising solution to this challenge. However, the non-Newtonian nature of blood, with its high viscosity a
Micromanipulation systems leverage automation and robotic technologies to improve the precision, repeatability, and efficiency of various tasks at the microscale. However, current approaches are typically limited to specific objects or tasks, which necessitates the use of custom tools and specialize
This study proposes an optoelectronic navigation strategy leveraging Ag-SiO<inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> microspheres as “microtruck” to overcome the limitations of traditional optoelectronic tweezers (OET) in manipulating nega
In recent years, capsule robots have gained wide acceptance among doctors and patients for the examination of gastrointestinal diseases due to their non-invasive, safe, and painless advantages. However, the image resolution captured by capsule robots is limited by space size and power, which hinders
As a medical microrobot, magnetic-controlled capsule robots (MCRs) are pivotal in internal diagnostics and therapeutic interventions. Achieving high-precision localization of MCRs is essential for the successful execution of medical procedures. This paper introduces a novel Dung Beetle Optimizer (DB…
Optoelectronic tweezers (OET) has shown great promise in various applications, especially in the precise manipulation of microparticles and microorganisms on a micron and nanometer scale. This technology significantly enhances the efficiency of single-cell sorting and the development of antibody-bas…
Magnetic microrobots exhibit enormous potential in targeted drug delivery owing to the remote wireless manipulation and minimum invasion for medical treatment. High degree of freedom offers the magnetic propelled robots extraordinary application prospect since they can be controlled precisely when d…
The untethered microrobots driven by multiple external physics fields have promising ability in minimally invasive disease treatments. One common type of the driving fields is gradient magnetic field, which can provide microrobots with adequate driving force in complicated environment. In this study…
This work presents a novel electrical method, implemented in the form of a microfluidic device, for cell arraying and target cell lysis. The microfluidic device contains a micro-well array on the photoconductive layer based on the optoelectronic tweezers (OET) method, where parallel cell manipulatio…
Macrophage immunotherapy is a promising clinical approach to treat cancer. However, low targeting efficiency severely limits the immunotherapeutic effect of macrophages. Here, we report a unique macrophage robot that can target and kill cancer cells using a combination of external acoustic and magne…
Magnetic-controlled micro-robots have promising applications in disease therapy due to their high targetability and drug utilization. Due to their unique deformable and divisible properties, ferrofluid robots have gained much attention in microchemical reaction chips and micromanipulation. This lett
Micro-nano robots with low invasiveness and high drug utilization are considered a promising approach for tumor therapy. However, individual micro-nano robots are limited in terms of motility, drug-carrying capacity, and environmental adaptability. This study proposes a clustering control strategy f
Non-contact manipulation technology has extensive application in the manipulation and fabrication of micro/nanomaterials. However, the manipulation devices are often precise and complex, operated only by professionals and subject to site constraints. We propose a simple optoelectronic tweezer platfo…
Microbubble-induced acoustic microstreaming for efficient on-chip micromanipulation is widely developed in biological applications. However, it is still challenging to simultaneously transport, trap, and rotate single cells using one device in a biocompatible manner, while expensive and bulky tradit…
Micro-nano-robots are considered to be a promising platform for drug delivery in biological organisms, but there are still urgent technical problems in biocompatibility and degradability of 3D-printed-based micro-robots that need to be solved. Therefore, in this paper, we design a magnetized bio-hyb…
Magnetic microrobots can be propelled precisely and wirelessly in vivo using magnetic field for targeted drug delivery and early detection. They are promising for clinical trials since magnetic fields are capable of penetrating most materials with minimal interaction, and are nearly harmless to huma…
Sonoporation, which typically employs acoustic cavitation microbubbles, can enhance the permeability of the cell membrane, allowing foreign matter to enter cells across the natural barriers. However, the diameter nonuniformity and random distribution of microbubbles make it difficult to achieve cont…
Circulating tumor cells (CTCs) are the primary cause of tumor metastasis after surgery. Metastatic tumor recurrence is the leading reason of cancer death. It is prerequisite to develop a platform for CTCs separation to predict the cancer cell transfer in important organs. Herein, a novel acoustic mi…
In this paper, we present a magnetized cell-robot using macrophages as templates, which can be controlled under a strong gradient magnetic field, to approach and kill cancer cells in both vitro and vivo environment. Firstly, we establish a magnetic control system using only four coils which can gene…
We propose an innovative design of microrobot, which can achieve donor cell suction, delivery and injection in a mammalian oocyte on microfluidic chip. The microrobot body contains a hollow space that produces suction and ejection forces for injection of cell nuclei using a nozzle at the tip of the…
The capability to precisely rotate the cells and other microscale objects is invaluable in biomedicine, bioengineering, and biophysics. We propose a novel on-chip three-dimension (3D) cell rotation method using whirling flows generated by oscillating asymmetrical microstructures. In an acoustic fiel…