102 accepted papers
Medical visual question answering models often face potential train-test distribution shifts that hinder generalization across unseen imaging and linguistic patterns. To address this challenge, we propose a dual-level confidence based framework (DuCoR) that achieves implicit self-refinement through
Recent advances in multimodal large language models (MLLMs) have catalyzed transformative progress in affective computing, enabling models to exhibit emergent emotional intelligence. Despite substantial methodological progress, current emotional benchmarks remain limited, as it is still unknown: (a)…
LLMs hold great promise for healthcare applications, but fast-changing medical knowledge can quickly make their outputs outdated or inaccurate, limiting use in high-stakes settings. Model editing can update LLMs without full retraining, but parameter-based methods often break locality and are risky …
Accurate identification of protein active sites at the residue level is crucial for understanding protein function and advancing drug discovery. However, current methods face two critical challenges: vulnerability in single-instance prediction due to sparse training data, and inadequate modality rel
Large vision-language models have achieved remarkable progress in visual reasoning, yet most existing systems rely on single-step or text-only reasoning, limiting their ability to iteratively refine understanding across multiple visual contexts. To address this limitation, we introduce a new multi-r…
Electroencephalography (EEG) is a noninvasive technique for measuring brain electrical activity that supports a wide range of brain-computer interaction applications. Motivated by the breakthroughs of Large Language Models (LLMs), recent efforts have begun to explore Large EEG foundation Models trai…
Distinguishing between extremely similar diseases is a critical and challenging aspect of clinical decision-making. Traditional classification, contrastive learning, and Large Language Models (LLMs) based methods fail to detect the subtle clues necessary for differentiation. This task demands comple…
Temporal knowledge graph reasoning aims to predict future events with knowledge of existing facts and plays a key role in various downstream tasks. Previous methods focused on either graph structure learning or semantic reasoning, failing to integrate dual reasoning perspectives to handle different…
Diffusion models have demonstrated powerful capability as a versatilist for dense vision tasks, yet the generalization ability to unseen domains remains rarely explored. This paper presents HarDiff, an efficient frequency learning scheme, so as to advance generalizable paradigms for diffusion based…
The recent advancements in language models have significantly catalyzed progress in computational biology. A growing body of research strives to construct unified foundation models for single-cell biology, with language models serving as the cornerstone. In this paper, we systematically review the d…
Hallucination has emerged as a critical challenge for large language models (LLMs) and large vision-language models (LVLMs), particularly in high-stakes medical applications. Despite its significance, dedicated research on medical hallucination remains unexplored. In this survey, we first provide a…
Recent studies have demonstrated the feasibility of modeling single-cell data as natural languages and the potential of leveraging powerful large language models (LLMs) for understanding cell biology. However, a comprehensive evaluation of LLMs' performance on language-driven single-cell analysis ta…
Diffusion-based virtual staining methods of histopathology images have demonstrated outstanding potential for stain normalization and cross-dye staining (e.g., hematoxylin-eosin to immunohistochemistry). However, achieving pathology-correct cross-dye virtual staining with versatile tone controls pos…
Image restoration is a fundamental task in computer vision and machine learning, which learns a mapping between the clear images and the degraded images under various conditions (e.g., blur, low-light, haze). Yet, most existing image restoration methods are highly restricted by the requirement of de…
Biomedical entity linking (BioEL) aims at mapping biomedical mentions to pre-defined entities. While extensive research efforts have been devoted to BioEL, applying large language models (LLMs) for BioEL has not been fully explored. Previous attempts have revealed difficulties when directly applying
Sequential Recommender Systems (SRS), which model a user's interaction history to predict the next item of interest, are widely used in various applications. However, existing SRS often struggle with low-popularity items, a challenge known as the long-tail problem. This issue leads to reduced serend…
Domain generalization aims to train models that perform robustly on unseen target domains without access to target data. The realm of vision-language foundation model has opened a new venue owing to its inherent out-of-distribution generalization capability. However, the static alignment to class-l…
Memes have emerged as a popular form of multimodal online communication, where their interpretation heavily depends on the specific context in which they appear. Current approaches predominantly focus on isolated meme analysis, either for harmful content detection or standalone interpretation, overl
Jailbreak attacks craft specific prompts or append adversarial suffixes to prompts, thereby inducing language models to generate harmful or unethical content and bypassing the model’s safety guardrails. With the recent blossom of large language models (LLMs), there’s a growing focus on jailbreak att…
Night-time scene segmentation is a critical yet challenging task in the real-world applications, primarily due to the complicated lighting conditions. However, existing methods lack sufficient generalization ability to unseen nigh-time scenes with varying illumination.In light of this issue, we focu…
Diagnosis based on Electronic Health Records (EHRs) often struggles with data scarcity and privacy concerns. To address these issues, we introduce RareSyn, an innovative data synthesis approach designed to augment and de-identify EHRs, with a focus on rare diseases. The core insight of RareSyn invol
AI for tumor segmentation is limited by the lack of large, voxel-wise annotated datasets, which are hard to create and require medical experts. In our proprietary JHH dataset of 3,000 annotated pancreatic tumor scans, we found that AI performance stopped improving after 1,500 scans. With synthetic d…
Recent advances in large language models have demonstrated remarkable performance on Contextual Question Answering (CQA). However, prior approaches typically employ elaborate reasoning strategies regardless of question complexity, leading to low adaptability. Recent efficient test-time scaling metho
In this paper, we re-introduce the Curse of Depth, a concept that re-introduces, explains, and addresses the recent observation in modern Large Language Models (LLMs) where deeper layers are much less effective than expected. We first confirm the wide existence of this phenomenon across the most pop…
The recent rise of Large Reasoning Models (LRMs) has significantly improved multi-step reasoning performance, but often at the cost of generating excessively long reasoning chains. This paper revisits the efficiency of such reasoning processes through an information-theoretic lens, revealing a funda…
Large Language Models (LLMs) have demonstrated exceptional capabilities across diverse natural language processing (NLP) tasks. The release of open-source LLMs like LLaMA and Qwen has triggered the development of numerous fine-tuned models tailored for various tasks and languages. In this paper, we…
The visual question localized-answering (VQLA) system has garnered increasing attention due to its potential as a knowledgeable assistant in surgical education. Apart from providing text-based answers, VQLA can also pinpoint the specific region of interest for better surgical scene understanding. Al…
Although biomedical entity linking (BioEL) has made significant progress with pre-trained language models, challenges still exist for fine-grained and long-tailed entities. To address these challenges, we present BioELQA, a novel model that treats Biomedical Entity Linking as Multiple Choice Questio…
The bias of disease prediction in Large Language Models (LLMs) is a critical yet underexplored issue, with potential implications for healthcare outcomes and equity. As LLMs increasingly find applications in healthcare, understanding and addressing their biases becomes paramount. This study focuses…
Semi-supervised learning (SSL), as one of the dominant methods, aims at leveraging the unlabeled data to deal with the annotation dilemma of supervised learning, which has attracted much attentions in the medical image segmentation. Most of the existing approaches leverage a unitary network by conv…
In recent years, there has been a growing interest in exploring dialogues with more complex goals, such as negotiation, persuasion, and emotional support, which go beyond traditional service-focused dialogue systems. Apart from the requirement for much more sophisticated strategic reasoning and comm…
Federated learning (FL) is a machine learning paradigm in which distributed local nodes collaboratively train a central model without sharing individually held private data. Existing FL methods either iteratively share local model parameters or deploy co-distillation. However, the former is highly s…
Most existing federated learning (FL) methods for medical image analysis only considered intramodal heterogeneity, limiting their applicability to multimodal imaging applications. In practice, it is not uncommon that some FL participants only possess a subset of the complete imaging modalities, posi…
Multi-task visual scene understanding aims to leverage the relationships among a set of correlated tasks which are solved simultaneously by embedding them within a uni- fied network. However most existing methods give rise to two primary concerns from a task-level perspective: (1) the lack of task-i…
Biomedical entity linking (BioEL) has achieved remarkable progress with the help of pre-trained language models. However, existing BioEL methods usually struggle to handle rare and difficult entities due to long-tailed distribution. To address this limitation, we introduce a new scheme kNN-BioEL, wh…
Dialogue policy learning (DPL) aims to determine an abstract representation (also known as action) to guide what the response should be. Typically, DPL is cast as a sequential decision problem across a series of predefined action candidates. However, such static and narrow actions can limit response…
The first 24 hours’ medication plan is critical to patients with serious or life-threatening illnesses and injuries. An appropriate medication can result in a lower mortality, a shorter length stay and a higher APACHE score. However, in clinical practice, the medication plan is often error-prone, es…
Sequential recommender systems (SRS) aim to predict users' subsequent choices based on their historical interactions and have found applications in diverse fields such as e-commerce and social media. However, in real-world systems, most users interact with only a handful of items, while the majority…
The emerging vision foundation model (VFM) has inherited the ability to generalize to unseen images. Nevertheless, the key challenge of domain-generalized semantic segmentation (DGSS) lies in the domain gap attributed to the cross-domain styles, i.e., the variance of urban landscape and environment…
Domain generalized medical image segmentation requires models to learn from multiple source domains and generalize well to arbitrary unseen target domain. Such a task is both technically challenging and clinically practical, due to the domain shift problem (i.e., images are collected from different…
Artificial intelligence (AI)-aided disease prediction has gained extensive research interest due to its capability to support clinical decision-making. Existing works mainly formulate disease prediction as a multi-label classification problem and use historical Electronic Medical Records (EMR) to tr…
Large language models (LLMs) have demonstrated remarkable capabilities in language understanding and generation, leading to their widespread adoption across various fields. Among these, the medical field is particularly well-suited for LLM applications, as many medical tasks can be enhanced by LLMs.…
Catastrophic forgetting remains a core challenge in continual learning (CL), where the models struggle to retain previous knowledge when learning new tasks. While existing replay-based CL methods have been proposed to tackle this challenge by utilizing a memory buffer to store data from previous tas…
The impressive capabilities of large language models (LLMs) have attracted extensive interests of applying LLMs to medical field. However, the complex nature of clinical environments presents significant hallucination challenges for LLMs, hindering their widespread adoption. In this paper, we addres…
Knowledge graph completion (KGC) is a widely used method to tackle incompleteness in knowledge graphs (KGs) by making predictions for missing links. Description-based KGC leverages pre-trained language models to learn entity and relation representations with their names or descriptions, which shows…
Medical insurance fraud has always been a crucial challenge in the field of healthcare industry. Existing fraud detection models mostly focus on offline learning scenes. However, fraud patterns are constantly evolving, making it difficult for models trained on past data to detect newly emerging frau…
Financial fraud is one of the most significant social issues and has caused tremendous property losses. Graph neural networks (GNNs) have been applied to anti-fraud practices and achieved decent results. However, recent researches have discovered flaws in the robustness of fraud-detection models bas…
Disease grading is a crucial task in medical image analysis. Due to the continuous progression of diseases, i.e., the variability within the same level and the similarity between adjacent stages, accurate grading is highly challenging. Furthermore, in real-world scenarios, models trained on limited…
The rapid development of intelligent systems for eye disease diagnosis decreases the risk of people suffering from vision impairment. However, the superior discrimination ability of existing retinal disease diagnosis methods heavily relies on the large-scale high-quality annotations. In this work, w…
Multi-modal sarcasm detection (MSD), which aims to identify whether a given sample with multi-modal information (i.e., text and image) is sarcastic, has garnered widespread attention. Recent approaches focus on designing sophisticated architectures or mechanisms to extract sarcastic cues from entire…
Visual prompting of large vision language models such as CLIP exhibits intriguing zero-shot capabilities. A manually drawn red circle commonly used for highlighting can guide CLIP's attention to the surrounding region to identify specific objects within an image. Without precise object proposals how…
Multiple instance learning (MIL)-based framework has become the mainstream for processing the whole slide image (WSI) with giga-pixel size and hierarchical image context in digital pathology. However these methods heavily depend on a substantial number of bag-level labels and solely learn from the o…
Automatic evaluation of natural language generation (NLG) tasks has gained extensive research interests, since it can rapidly assess the performance of large language models (LLMs). However, automatic NLG evaluation struggles with medical QA because it fails to focus on the crucial correctness of me…
Due to the outstanding capability for data generation, Generative Adversarial Networks (GANs) have attracted considerable attention in unsupervised learning. However, training GANs is difficult, since the training distribution is dynamic for the discriminator, leading to unstable image representatio…
Recent text-to-image diffusion models have demonstrated an astonishing capacity to generate high-quality images. However, researchers mainly studied the way of synthesizing images with only text prompts. While some works have explored using other modalities as conditions, considerable paired data, e…
The cross-domain text-to-SQL task aims to build a system that can parse user questions into SQL on complete unseen databases, and the single-domain text-to-SQL task evaluates the performance on identical databases. Both of these setups confront unavoidable difficulties in real-world applications. To…
Vision Transformers have recently shown impressive performances on medical image segmentation. Despite their strong capability of modeling long-range dependencies, the current methods still give rise to two main concerns in a class-level perspective: (1) intra-class problem: the existing methods lac…
Automatic diagnosis (AD), a critical application of AI in healthcare, employs machine learning techniques to assist doctors in gathering patient symptom information for precise disease diagnosis. The Transformer-based method utilizes an input symptom sequence, predicts itself through auto-regression…
Generative Adversarial Networks (GANs) have shown compelling results in various tasks and applications in recent years. However, mode collapse remains a critical problem in GANs. In this paper, we propose a novel training pipeline to address the mode collapse issue of GANs. Different from existing m…
The multi-turn doctor-patient dialogue includes rich medical knowledge, like the symptoms of the patient, the diagnosis and medication suggested by the doctor. If mined and represented properly, such medical knowledge can benefit a large range of clinical applications, including diagnosis assistance…
Training Generative Adversarial Networks (GANs) remains a challenging problem. The discriminator trains the generator by learning the distribution of real/generated data. However, the distribution of generated data changes throughout the training process, which is difficult for the discriminator to…
Efficient detectors for edge devices are often optimized for parameters or speed count metrics, which remain in weak correlation with the energy of detectors. However, some vision applications of convolutional neural networks, such as always-on surveillance cameras, are critical for energy constra…
Medical insurance plays a vital role in modern society, yet organized healthcare fraud causes billions of dollars in annual losses, severely harming the sustainability of the social welfare system. Existing works mostly focus on detecting individual fraud entities or claims, ignoring hidden conspira…
Event causality identification (ECI) aims to identify the causal relationship between events, which plays a crucial role in deep text understanding. Due to the diversity of real-world causality events and difficulty in obtaining sufficient training data, existing ECI approaches have poor generalizab…
Click-based interactive segmentation (IS) aims to extract the target objects under user interaction. For this task, most of the current deep learning (DL)-based methods mainly follow the general pipelines of semantic segmentation. Albeit achieving promising performance, they do not fully and explici…
Various stuff and things in visual data possess specific traits, which can be learned by deep neural networks and are implicitly represented as the visual prior, e.g., object location and shape, in the model. Such prior potentially impacts many vision tasks. For example, in conditional image synthes…
Multimodal magnetic resonance imaging (MRI) provides complementary information for sub-region analysis of brain tumors. Plenty of methods have been proposed for automatic brain tumor segmentation using four common MRI modalities and achieved remarkable performance. In practice, however, it is common…
Credit card fraud incurs a considerable cost for both cardholders and issuing banks. Contemporary methods apply machine learning-based classifiers to detect fraudulent behavior from labeled transaction records. But labeled data are usually a small proportion of billions of real transactions due to e…
Semi-supervised learning improves data efficiency of deep models by leveraging unlabeled samples to alleviate the reliance on a large set of labeled samples. These successes concentrate on the pixel-wise consistency by using convolutional neural networks (CNNs) but fail to address both global learni…
Inspired by the great success of deep neural networks, learning-based methods have gained promising performances for metal artifact reduction (MAR) in computed tomography (CT) images. However, most of the existing approaches put less emphasis on modelling and embedding the intrinsic prior knowledge…
Event detection is challenging in real-world application since new events continually occur and old events still exist which may result in repeated labeling for old events. Therefore, incremental event detection is essential where a model continuously learns new events and meanwhile prevents perform…
Unsupervised pretraining based on contrastive learning has made significant progress recently and showed comparable or even superior transfer learning performance to traditional supervised pretraining on various tasks. In this work, we first empirically investigate when and why unsupervised pretrain…
Fast screening and diagnosis are critical in COVID-19 patient treatment. In addition to the gold standard RT-PCR, radiological imaging like X-ray and CT also works as an important means in patient screening and follow-up. However, due to the excessive number of patients, writing reports becomes a he…
"Research into Few-shot Semantic Segmentation (FSS) has attracted great attention, with the goal to segment target objects in a query image given only a few annotated support images of the target class. A key to this challenging task is to fully utilize the information in the support images by explo…
Distant supervision (DS) is a strong way to expand the datasets for enhancing relation extraction (RE) models but often suffers from high label noise. Current works based on attention, reinforcement learning, or GAN are black-box models so they neither provide meaningful interpretation of sample sel…
"High inter-equipment variability and expensive examination costs of brain imaging remain key challenges in leveraging the heterogeneous scans effectively. Despite rapid growth in image-to-image translation with deep learning models, the target brain data may not always be achievable due to the spec…
Providing Emotional Support (ES) to soothe people in emotional distress is an essential capability in social interactions. Most existing researches on building ES conversation systems only considered single-turn interactions with users, which was over-simplified. In comparison, multi-turn ES convers…
Multi-modal entity alignment aims to identify equivalent entities between two different multi-modal knowledge graphs, which consist of structural triples and images associated with entities. Most previous works focus on how to utilize and encode information from different modalities, while it is not…
Understanding the source of the superior generalization ability of NNs remains one of the most important problems in ML research. There have been a series of theoretical works trying to derive non-vacuous bounds for NNs. Recently, the compression of information stored in weights (IIW) is proved to p…
Prompt-based fine-tuning for pre-trained models has proven effective for many natural language processing tasks under few-shot settings in general domain. However, tuning with prompt in biomedical domain has not been investigated thoroughly. Biomedical words are often rare in general domain, but qui…
With the rise of telemedicine, the task of developing Dialogue Systems for Medical Diagnosis (DSMD) has received much attention in recent years. Different from early researches that needed to rely on extra human resources and expertise to build the system, recent researches focused on how to build D…
Low-shot (one/few-shot) segmentation has attracted increasing attention as it works well with limited annotation. State-of-the-art low-shot segmentation methods on natural images usually focus on implicit representation learning for each novel class, such as learning prototypes, deriving guidance fe…
Complex backgrounds and similar appearances between objects and their surroundings are generally recognized as challenging scenarios in Salient Object Detection (SOD). This naturally leads to the incorporation of depth information in addition to the conventional RGB image as input, known as RGB-D SO…
For the single image rain removal (SIRR) task, the performance of deep learning (DL)-based methods is mainly affected by the designed deraining models and training datasets. Most of current state-of-the-art focus on constructing powerful deep models to obtain better deraining results. In this paper,…
This paper explores the task of Difficulty-Controllable Question Generation (DCQG), which aims at generating questions with required difficulty levels. Previous research on this task mainly defines the difficulty of a question as whether it can be correctly answered by a Question Answering (QA) syst…
For task-oriented dialog systems, training a Reinforcement Learning (RL) based Dialog Management module suffers from low sample efficiency and slow convergence speed due to the sparse rewards in RL. To solve this problem, many strategies have been proposed to give proper rewards when training RL, bu…
With the need of fast retrieval speed and small memory footprint, document hashing has been playing a crucial role in large-scale information retrieval. To generate high-quality hashing code, both semantics and neighborhood information are crucial. However, most existing methods leverage only one of…
In medical image analysis, it is typical to collect multiple annotations, each from a different clinical expert or rater, in the expectation that possible diagnostic errors could be mitigated. Meanwhile, from the computer vision practitioner viewpoint, it has been a common practice to adopt the grou…
Unsupervised domain adaption has proven to be an effective approach for alleviating the intensive workload of manual annotation by aligning the synthetic source-domain data and the real-world target-domain samples. Unfortunately, mapping the target-domain distribution to the source-domain unconditio…
Joint extraction of entities and relations from unstructured texts is a crucial task in information extraction. Recent methods achieve considerable performance but still suffer from some inherent limitations, such as redundancy of relation prediction, poor generalization of span-based extraction and…
Existing unsupervised document hashing methods are mostly established on generative models. Due to the difficulties of capturing long dependency structures, these methods rarely model the raw documents directly, but instead to model the features extracted from them (e.g. bag-of-words (BOG), TFIDF).…
Convolutional Neural Networks (CNNs) have advanced existing medical systems for automatic disease diagnosis. However, a threat to these systems arises that adversarial attacks make CNNs vulnerable. Inaccurate diagnosis results make a negative influence on human healthcare. There is a need to investi…
Knowledge Graph (KG) alignment is to discover the mappings (i.e., equivalent entities, relations, and others) between two KGs. The existing methods can be divided into the embedding-based models, and the conventional reasoning and lexical matching based systems. The former compute the similarity of…
Embedding-based entity alignment has been widely investigated in recent years, but most proposed methods still rely on an ideal supervised learning setting with a large number of unbiased seed mappings for training and validation, which significantly limits their usage. In this study, we evaluate th…
Deep convolutional neural networks (DCNNs) have contributed many breakthroughs in segmentation tasks, especially in the field of medical imaging. However, domain shift and corrupted annotations, which are two common problems in medical imaging, dramatically degrade the performance of DCNNs in practi…
Deep clustering which adopts deep neural networks to obtain optimal representations for clustering has been widely studied recently. In this paper, we propose a novel deep image clustering framework to learn a category-style latent representation in which the category information is disentangled fro…
Active learning, reducing the cost and workload of annotations, attracts increasing attentions from the community. Current active learning approaches commonly adopted uncertainty-based acquisition functions for the data selection due to their effectiveness. However, data selection based on uncertain…
Counterfactual learning for dealing with missing-not-at-random data (MNAR) is an intriguing topic in the recommendation literature, since MNAR data are ubiquitous in modern recommender systems. Instead, missing-at-random (MAR) data, namely randomized controlled trials (RCTs), are usually required by…
We introduce a one-shot segmentation method to alleviate the burden of manual annotation for medical images. The main idea is to treat one-shot segmentation as a classical atlas-based segmentation problem, where voxel-wise correspondence from the atlas to the unlabelled data is learned. Subsequently…
Recent generative adversarial network (GAN) based methods (e.g., CycleGAN) are prone to fail at preserving image-objects in image-to-image translation, which reduces their practicality on tasks such as domain adaptation. Some frameworks have been proposed to adopt a segmentation network as the auxil…
Computed tomography (CT) can provide a 3D view of the patient's internal organs, facilitating disease diagnosis, but it incurs more radiation dose to a patient and a CT scanner is much more cost prohibitive than an X-ray machine too. Traditional CT reconstruction methods require hundreds of X-ray pr…
Synthesized medical images have several important applications, e.g., as an intermedium in cross-modality image registration and as supplementary training samples to boost the generalization capability of a classifier. Especially, synthesized CT data can provide X-ray attenuation map for radiation t…