47 accepted papers
Recent progress in stereo-based 3D Gaussian Splatting (3DGS) SLAM has enabled small-scale robots, which are too small to carry depth cameras, to achieve localization and reconstruct photorealistic scenes with high-speed rendering. However, initializing 3D Gaussians from binocular vision still requir
For individuals with limited mobility who are bedridden for extended periods, providing comfortable assisted feeding services is one of the most significant actions to enhance their quality of life. Despite the development of various feeding assistive robots, there remain limitations in terms of int
Various forms of biohybrid robots have been developed; however, creating robots with multiple degrees of freedom remains a challenging task. In this paper, we developed a multi-joint biohybrid robot by using skeletal muscle tissue. To achieve this, we first developed a modular bio-actuator actuated
Magnetic helical microrobots have attracted considerable attraction in microscale targeted delivery due to their high propulsion efficiency and movement flexibility. However, for biomedical applications in unstructured and multibranched liquid environments, the capabilities of high swimming performa
Tactile information is the research hotspot of wearable flexible sensors due to its importance and complexity. With the innovation of wearable technology and robotics in healthcare, researchers are increasingly integrating wearable flexible sensors on the front end of robots to reproduce the hand ta…
Embodying in vitro biological neural networks (BNNs) with robots to explore the rise of intelligence in these simpler models and to endow robots with biological intelligence has been attracting increasing attention in the fields of neuroscience and robotics. However, current research suffers from un
Microfluidic printing provides a novel tool to facilitate the bulk assembly of cell-aligned microfibers for the fabrication of artificial skeletal muscle structure. However, due to the poor controllability for the deposition position of the microfiber, it is still difficult to realize the anisotropi
In this paper, we propose a system for real-time rat pose estimation based on stereo vision. The system is dedicated to robot-rat interaction research. First, we design a lightweight, high-resolution network (RRKDNet) for keypoint detection of the rat. The network is trained on a dataset of rat imag…
In this letter, we propose a motion generation strategy using imitation learning (IL) for biomimetic robots to interact with animals in a more natural manner. We previously developed a bioinspired spine mechanism allowing the robot to mimic rat motion closely. Thanks to the spine morphology, we esta
Whiskers of some animals, such as rats and cats, can actively sense stimuli from their surrounding environment. Such a capability is attractive for intelligent mobile robots. However, an artificial whisker with similar abilities has not been fully developed so that the robots acquire their surroundi
In this paper, we fabricated a soft sensor based on PEDOT:PSS for thin film structure. The developed soft sensor can measure the contraction force at real time to be embedded in a modular bio-actuator [1]. The modular actuator generated contraction forces at 0.3 mN when applying electric pulse stimu…
In this paper, we propose an automatic robot-rat interaction framework that enables a robotic rat to realize real-time localization, tracking and movement analysis of a laboratory rat. Specifically, we combine an object detector with stereo matching to achieve fast localization of the laboratory rat…
Fabricated cellular micro-scaffold that recapitulates natural extracellular matrix (ECM) has shown huge potential in the study of cell behaviors. However, the reproducing of the physiological morphology with high efficiency and accuracy in the micro-scaffold still remains as a major challenge. Here,
In spite of recent high attention of the biohybrid robot system, the previous researches focused on actuation system depend on simple on/off control without feedback control. To solve this problem, we proposed a soft sensor for feedback control of a bio-actuator driven by skeletal muscle. The propos…
Many previous works have facilitated muscle cell (C2C12) alignment to form fiber-like cell structures. However, there still remains a challenge how to induce C2C12 myoblasts in the cell structures to differentiate into matured myocytes to form a functional muscle tissue, while external mechanical st…
In this paper, we have constructed actively perfusable multiple hepatic lobule-like vascular networks in a 3D cellular structure by using magnetic tweezers. Without well-organized channel networks, cells in a large 3D tissue cannot receive nutrients and oxygen from the channel, and therefore, the ce…
Tissue engineering is trying to use modular tissue micro-rings to construct artificial biological microtubes as substitute of autologous tissue tubes to alleviate the shortage of donor sources. However, because of the lack of effective assembly strategies, it is still challenging to achieve high-spe…
In this paper, we have fabricated a multilayered hepatic lobule-like vascular network in a 3D tissue using a heptapole magnetic tweezer. The tissue consists of cell-laden hydrogels with 3D channel networks. To fabricate multilayered channel system, magnetic hydrogel fibers were manipulated by a magn…
The research on rare cells makes a significant contribution to biology research and medical treatment for the application of diagnostic operation as well as prognoses treatment. Therefore, sorting them from heterogeneous mixtures is crucial and valuable. Traditional cell sorting methods featured wit…
Social interaction between a robot and rats is important since the robot can generate reproducible social behaviors across trials. However, lacking internal state feedback from the rat makes current robot-rat interaction a very preliminary level comparing with rat-rat interaction. Previous biologica…
Fabrication of vascular network is an important research for transporting required nutrients and oxygen to the artificial tissues. In this paper, we propose a novel method to construct a hepatic lobule-like vascular network in a 3D cellular structure. The network is simply constructed by three types…
Microgrippers play a significant role in manipulation of micro-objects. To achieve dexterous and precise manipulation, a microgripper is required to be compactly designed and embedded with sensing feedback. Meanwhile, to convert the sensor position into displacement of the microgripper, the embedded…
In this paper, we introduce a walking load control strategy with a cane-type robot for gait training. The population of elderly people is increasing in most of the developed countries, and there is a growing demand for caregivers. Assistive robots are expected as a solution to provide aid in order t…
This study presents the high-precision microinjection of fluorescent micro-gel beads into Caenorhabditis elegans trapped in a suction microchannel. In our previous works, we demonstrated survival microinjection by a conventional micromanipulation technique. However, the focal planes differed between…
The interaction test between a robotic rat and living rat is considered as a possible way to quantitatively characterize the rat sociality. In such robot-rat interactions, the robot should be designed to fully replicate a real rat in terms of morphological and behavioral characteristics. To address…
In this letter, we conducted a new method to fabricate channels inside cell structures for tissue engineering applications. A cell-embedded hydrogel is locally melted to fabricate channels inside cell structures. The fabricated channels can be used as vascular-like networks to supply nutrition and o
In micromanipulation, lots of methods have been developed to manipulate objects in microscale. However, few of them can be applied in both the transportation and the rotation of the micro objects. In this paper, we present a novel method to realize the non-contact transportation and rotation of the…
In this research, we fabricated movable toroidal cell structures inside a microfluidic device for tissue engineering applications. A photo-crosslinkable biodegradable hydrogel gelatin methacrylate (GelMA) was employed to encapsulate biological cells for assembling cell structures. The UV light power…
Helical structure assembled by hydrogel microfibers is significant for culture of smooth muscle cells. However, the helical structure is only fabricated at the macroscale, while the fabrication of helical microstructure is still a challenge due to the lack of assembly method. In this paper, we propo…
This paper describes a octo-rotor unmanned aerial vehicle (UAV) with one degree of freedom (DoF) manipulator for bridge inspection. The UAV has an ability to contact bridge pier to conduct hammering test. To control contact force applied by the UAV to the bridge pier, one DoF is enough for the manip…
It is of great importance to pick up a single carbon nanotube (CNT) from a bulk of CNTs for nanodevice fabrication. In this study, we have proposed a nanorobotic manipulation system allowing automated pick-up of CNTs based on visual feedback. We utilize histogram normalization for automatic binariza…
Constructing 3D cell module with certain shape and high cell density is a very important issue for artificial tissue engineering. In this letter, we present a novel method of fabricating compact microtissue with gear-like shape by electrodepositing of Ca <sup xmlns:mml="http://www.w3.org/1998/Math/M
In vitro tissues are significant biological substitute for drug test, cell morphogenesis exploration and organ transplantation. In this letter, a novel microrobotic bioassembly method is proposed to engineer 3-D cellular structure, which can be utilized to culture in vitro tissue with microstructura
Vascular-like microtube takes an important role in delivering oxygen and nutrient to keep cell alive in the generated tissue. In this paper, we present an automated micromanipulation system to assemble 2-D gel micro-rings to vascular-like microtubes by means of generating and controlling microbubble
Alginate hydrogel microfibers are a promising cell-laden module for three-dimensional (3-D) assembly to build cellular structures. However, it is still a challenge to manipulate them for microassembly. In this letter, we report a novel magnetic control method to handle this challenge. To enhance the
This paper presents a novel In situ nanomanipulation integrated with scanning electron microscope- computed tomography (SEM-CT) imaging system for 3D nanomanipulation. In our previous works, a nanorobotic manipulation system was established inside an environmental-SEM (E-SEM) for water-contained sam
This paper proposes a quasi-passive dynamic autonomous control (Q-PDAC) for a three-dimensional (3-D) bipedal gait of humanoid robots from start points to goal points. The major approach for 3-D traveling is currently footstep planning by a constantly stable gait with an emphasis on its accurate and…
In this paper, we propose a new method to assemble microstructures with biological cells towards in vitro 3D cellular structures. The proposed assembly method uses self-assembly process of magnetized toroidal microstructures. Biocompatible toroidal hydrogel microstructures are prepared by electrodep…
Conventional humanoids have achieved walking and running by independent controllers, even though a transition between these independent motions should be added to connect them while ensuring stability. In contrast, human selects walking/running at low/high speed in terms of energy efficiency, and tr
Fabrication of artificial blood vessels in micro scale significantly benefits the regeneration of functional human vascular networks. In this paper, we develop an efficient multi-microrobotic system with an innovative motorized sample holder (MSH) and two manipulators. Air is injected into the solut…
In this study, cell-laden alginate-poly-L-lysine (PLL) hydrogel structures with arbitrary shapes were constructed based on electrodeposition method. Electrolysis of water in alginate solutions with calcium carbonate particles induced alginate gelation on micro-patterned anode electrode, and cell-lad…
In this paper, we conducted a new method to assemble microstructures inside a droplet named “Lab in a Droplet (LiD)”. The method can realize the assembly of micro-nano structures inside a droplet size. The surface tension is used to assemble microstructures automatically. Micro-scale or nano-scale o…
This paper describes a magnetic resonance imaging (MRI) compatibility assessment of our lower-extremity motion simulator called LoMS which provides gait-like motion for a wearer within his/her lying posture during functional MRI (fMRI) imaging. We confirmed that the existence and the movement of LoM…
Walking capability composed of stability and efficiency is one of the most important issues in the field of humanoid robots. An effective swing of the arms is expected to enhance the walking capability under the constraints from the limited body. We propose an arm-swing method to enhance the stabili…
This study presents the survival microinjection into Caenorhabditis elegans (C. elegans) with in vivo observation based on micromanipulation. The microinjections were achieved with micro-gel beads which are enable to encapsulate chemicals for injection. In this study, a fluorescent material was used…
Fall prevention is one of the most important functions of walking assistance devices for user's safety. It is preferable that these devices obviates factors which induce falling over rather than helping them recovering from falling motion. Tandem stance, where both legs form a line along walking dir…
Due to the poor controllability in hydrogels, Hydrogels-based assembly to form larger 3D complex shapes is still a big challenge. In this paper, we have reported a novel “bottom-up” method to fabricate three-dimensional (3D) magnetic alginate microfibers (MAMs) assemblies with complex shapes. Specif…